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Orpheus API Reference

Natural language query question answer

POST Natural language query

https://api.wisecube.ai/orpheus/graphql

This API allows querying the knowledge graph using natural language queries.

BODY graphql

QUERY

query questionAnswer($query: String) {
 summaryInsights(engineID:"orpheus", searchInput: {
     query: $query, type: [QA]}) 
     {
        data {
            __typename
            ... on QAInsight {
        question
        answers {
          answer
          document {
            id
            title
            abs
            source
            index_name
            __typename
          }
          took
          context
          statistics
          probability
          __typename
        }
        __typename
      }
    }
    __typename
  }
}

GRAPHQL VARIABLES

{ "query" : "what is cancer" }

Example Request: Informational query

POST /orpheus/graphql HTTP/1.1 
Host: api.wisecube.ai 
Content-Type: application/json 
Content-Length: 387 

{"query":"query questionAnswer($query: String) {\n summaryInsights(engineID:\"orpheus\", searchInput: {\n     query: $query, type: [QA]}) \n     {\n        data {\n            __typename\n            ... on QAInsight {\n        question\n        answers {\n          answer\n          document {\n            id\n            title\n            abs\n            source\n            index_name\n            __typename\n          }\n          took\n          context\n          statistics\n          probability\n          __typename\n        }\n        __typename\n      }\n    }\n    __typename\n  }\n}","variables":{"query":"what is cancer"}}

Example Response

{
    "data": {
        "summaryInsights": [
            {
                "data": {
                    "__typename": "QAInsight",
                    "question": "what is cancer",
                    "answers": [
                        {
                            "answer": "Cancer is a complex illness characterized by the uncontrolled division of abnormal cells, which have the ability to invade nearby tissues and spread to other parts of the body. It is a leading cause of death globally and can affect various organs and systems, including the bladder, brain, breast, cervix, colorectal, esophageal, gastric, head and neck, hematologic, kidney, liver, lung, melanoma, pancreas, prostate, sarcomas, thyroid, and uterine. The cells in cancerous tumors divide without control, leading to the formation of malignant growths that can disrupt the normal functioning of the affected organ or tissue. Early detection and treatment are crucial in managing and potentially curing cancer.",
                            "document": [
                                {
                                    "id": "NCT02239575",
                                    "title": "Collection of Retrospective (Archival) Samples and Prospective Collection of Surplus Tissue and Blood Samples",
                                    "abs": "This study will enroll specimens from subjects diagnosed with various cancers and who have either RETROSPEFCTIVE  ARCHIVAL SAMPLES already undergone surgical resection of their tumor and have one or more formalin fixed and paraffin embedded FFPE blocks on file within the local or affiliated pathology archive replicate blocks from same tumor or blocks no longer required to be maintained on file  discard blocks or PROSPECTIVE SAMPLES are scheduled to undergo surgical treatment and who prior to scheduled surgery provide informed consent and donate a 10 20 ml blood sample After surgery surplus tissues including tumor and adjacent normal tissues not required for diagnosis will be collected Subject clinical information will be collected including basic demographic information medical history current cancer history and treatment A final pathology report will be obtained for each subject s surgical specimen In some instances and based on the cancer indications required longitudinal data may also be collected at a frequency of every 6 months to once per year Longitudinal data will include information on study subject survival and disease recurrence CANCER INDICATIONS Bladder Cancer  Urothelial carcinoma  nonpapillary Bladder Cancer  Urothelial carcinoma  papillary Brain Cancer  Astrocytoma Brain Cancer  Glioblastoma Brain Cancer  Medulloblastoma Breast Cancer  Ductal Carcinoma Breast Cancer  Lobular Carcinoma Cervical Cancer  Squamous Cell Carcinoma Colorectal Cancer  Adenocarcinoma Esophageal Cancer  Adenocarcinoma Gastric Cancer Head and Neck Cancer  Squamous Cell Carcinoma Hematologic Cancer  Acute Lymphocytic Leukemia ALL Hematologic Cancer  Acute Myeloid Leukemia AML Hematologic Cancer  Chronic Lymphocytic Leukemia CLL Hematologic Cancer  Diffuse Large B cell Lymphoma Hematologic Cancer  Multiple Myeloma MM Hematologic Cancer  Non Hodgkins Lymphoma NHL Kidney Cancer  Papillary Carcinoma Kidney Cancer  Renal cell Carcinoma Liver Cancer  Hepatocellular Carcinoma Lung Cancer  Adenocarcinoma Lung Cancer  Squamous Cell Cancer Melanoma Pancreatic Cancer  Ductal Adenocarcinoma Prostate Cancer  Adenocarcinoma Sarcomas Thyroid Cancer  Follicular Carcinoma Thyroid Cancer  Papillary Carcinoma Uterine Cancer  Endometrial Carcinoma",
                                    "source": "http://clinicaltrials.gov/ct2/show/NCT02239575",
                                    "index_name": "Clinical Trials",
                                    "__typename": "RelatedDocument"
                                },
                                {
                                    "id": "NCT06018935",
                                    "title": "A Cohort Establishment Study of Total Management of Ovarian Cancer (Including Fallopian Tube Cancer and Primary Peritoneal Cancer)",
                                    "abs": "A cohort establishment study of total management of ovarian cancer including fallopian tube cancer and primary peritoneal cancer  To investigate the effects of surgery chemotherapy maintenance therapy and related factors on the prognosis and quality of life of patients with ovarian cancer including fallopian tube cancer and primary peritoneal cancer  To study the postoperative recovery of patients with ovarian cancer including fallopian tube cancer and primary peritoneal cancer  perioperative complications adverse reactions after chemotherapy adverse reactions during targeted drug maintenance therapy and explore possible effective preventive measures The prognostic factors of ovarian cancer including fallopian tube cancer and primary peritoneal cancer were analyzed To study the efficacy and safety of PARPi in clinical application in patients with ovarian cancer including fallopian tube cancer and primary peritoneal cancer ",
                                    "source": "http://clinicaltrials.gov/ct2/show/NCT06018935",
                                    "index_name": "Clinical Trials",
                                    "__typename": "RelatedDocument"
                                },
                                
                          {...},
                          {...}
                  
                            ],
                            "took": 15.716960906982422,
                            "context": null,
                            "statistics": [
                                {
                                    "index_name": "Clinical Trials",
                                    "total_hits": 10000
                                },
                                {
                                    "index_name": "PubMed",
                                    "total_hits": 10000
                                }
                            ],
                            "probability": null,
                            "__typename": "Answer"
                        }
                    ]
                },
                "__typename": "Insight"
            }
        ]
    }
}



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